Gynecological Cancers
The Gynecological Cancers Research Program at the Center for Women’s Health and Reproductive Medicine at the University of Pennsylvania is dedicated to advancing the understanding, prevention, and treatment of cancers that affect the female reproductive system. Our research encompasses various gynecologic cancers, including ovarian, cervical, uterine, vaginal, and vulvar cancers. Through cutting-edge research and innovative clinical trials, our team aims to uncover the underlying mechanisms of these cancers, identify new biomarkers for early detection, and develop more effective, personalized treatment strategies.
Our multidisciplinary team of experts collaborates closely with oncologists, surgeons, pathologists, and geneticists to ensure a comprehensive approach to gynecologic cancer research. By leveraging advanced technologies such as genomic sequencing, immunotherapy, and targeted therapies, we strive to improve patient outcomes and quality of life. Our research also focuses on understanding the genetic and environmental risk factors associated with gynecologic cancers, aiming to develop preventive measures that can reduce the incidence of these diseases.
In addition to our laboratory and clinical research efforts, we are committed to translating our findings into tangible benefits for patients. Our clinical trials provide patients with access to the latest treatment options and innovative therapies, often before they are widely available. We also prioritize patient education and support, offering resources and guidance to help patients and their families navigate the complexities of cancer treatment and care.
Through our relentless pursuit of knowledge and our dedication to improving women’s health, the Gynecological Cancers Research Program at the Center for Women’s Health and Reproductive Medicine continues to make significant strides in the fight against gynecologic cancers. Our ultimate goal is to reduce the burden of these cancers and enhance the lives of women affected by them, both now and in the future.
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Penn Medicine receives funding to launch NAVIGATE
Penn Medicine has received funding from the HHS and Office on Women’s Health to launch NAVIGATE, a new Center of Excellence for PMOS (Polyendocrine Metabolic Ovarian Syndrome, formerly PCOS) — the most common endocrine disorder in reproductive-age women worldwide. Led by Dr. Anuja Dokras, an internationally recognized clinical and researcher in PMOS, the two-year project […]
Drs. Marisa Bartolomei & Cori Schreiber elected to National Academy of Medicine
Congratulations to Drs. Marisa Bartolomei & Cori Schreiber on their elections to the National Academy of Medicine. Election to the Academy is considered one of the highest honors in the fields of health and medicine and recognizes individuals who have demonstrated outstanding professional achievement and commitment to service. To see the full list of those […]
Dr. Kate O’Neill and the Uterus Transplant Program featured on Good Day Philadelphia
Dr. Kate O’Neill and Stephanie Collado were interviewed by Alex Holley and Karen Hepp on Good Day Philadelphia. Stephanie received a uterus transplant at Penn from a living donor and gave birth to a baby boy last year. Follow this link to watch the full interview.
Nicolas Plachta & Eric Rhon-Calderon interviewed by SSR
Dr. Nicolas Plachta & Dr. Eric Rhon-Calderon were interviewed for the latest SSR newsletter. Follow the links to read their interviews.
Eric Rhon-Calderon of the Bartolomei lab has a new paper published in JCI
Eric Rhon-Calderon of the Bartolomei lab recently had a paper published in the Journal of Clinical Investigation. The paper titled “Mouse offspring conceived by in vitro fertilization exhibit accelerated reproductive aging through premature ovarian insufficiency” was also accompanied by the editorial publication “Reproductive life after in vitro fertilization.” Both publications are linked below. https://www.jci.org/articles/view/201633 https://www.jci.org/articles/view/210577 […]
Congratulations, Natalie Brown on F30 project funding!
Natalie Brown, 5th year MD/Ph.D. student (who is going into the 3rd year of her Ph.D. in CAMB CPM) in Zolt Arany’s lab was recently awarded funding from NHLBI. Her project is centered on understanding how placental signals (hormones, proteases and extracellular vesicle cargo) reprogram the maternal heart during pregnancy. The goal is to better […]
Kristin Gerson – BWF 2026 Next Gen Pregnancy Initiative Recipient
The Burroughs Wellcome Fund (BWF) is pleased to announce the seven recipients of the 2026 Next Gen Pregnancy Initiative (NGP), a program supporting innovative research that advances understanding of pregnancy and pregnancy-related complications. The initiative invests in bold, interdisciplinary science aimed at improving outcomes for pregnant individuals and infants while deepening our understanding of the […]
5/22 is World Preeclampsia Day
Preeclampsia is a serious condition that can happen after the 20th week of pregnancy or after giving birth (called postpartum preeclampsia). In addition to causing high blood pressure, it can cause organs like the kidneys and liver to not work normally. Preeclampsia affects about 1 in 25 pregnancies in the United States. It is a […]
Women with this condition are often misdiagnosed. Its new name could help.
A new name for polycystic ovary syndrome (PCOS) to polyendocrine metabolic ovarian syndrome (PMOS) reflects growing recognition that the condition affects far more than reproductive health. Anuja Dokras, MD PhD, director of the Penn Polycystic Ovary Syndrome Center and the Founders Professor of Obstetrics and Gynecology led the effort behind the change. Many patients experience […]